Welcome to AskPharmaTutor Quiz of Basic Pharmacology I Follow the instructions below to attempt the quiz Choose one best option only Follow the timeline After attempting all the questions click on submit to get your result 1. Which of the following drugs may inhibit the hepatic microsomal P450 responsible for warfarin metabolism Cimetidine Ethanol Phenobarbital Rifampin None 2. Which of the following is a phase II drug metabolizing reaction? Acetylation Deamination Hydrolysis Oxidation None 3. Which of the following provides information about the variation in sensitivity of the drug within the population studied? Maximal efficacy Therapeutic index Drug potency Quantal dose response curve None 4. A good example of chemical antagonism Heparin & Protamine Protamine & Zinc Heparin & Prothrombin All of the above None 5. Phenylephrine causes Constriction of vessels in the nasal mucosa Increased gastric secretion and motility Increased skin temperature All of the above None 6. Distribution of drugs to specific tissues Is independent of blood flow to the organ Is independent of the solubility of the drug in that tissue Depends on the unbound drug concentration gradient between blood and tissue Has no effect on the half life of the drug None 7. The following are excreted faster in basic urine Weak acids Strong Acids Weak Bases None of the above None 8. All of the following are general mechanism of drug permeation except Aqueous diffusion Aqueous hydrolysis Lipid diffusion Pinocytosis None 9. Which of the following terms best describes a drug that blocks the action of epinephrine at its receptors by occupying those receptors without activating them? Pharmacological Antagonist Partial Agonist Physiological Antagonist Chemical Antagonist None 10. A physical process by which a weak acid becomes less water soluble and more lipid soluble at low pH is Distribution Elimination First pass effect Protonation None Welcome to AskPharmaTutor Quiz of Basic Pharmacology II Follow the instructions below to attempt the quiz Choose one best option only Follow the timeline After attempting all the questions click on submit to get your result 1. The renal clearance of insulin is used as a measurement of Effective renal blood flow Rate of renal drug excretion Active renal secretion Glomerular filtration rate None 2. Hydrolysis reactions are involved with the metabolism of following drugs, except Procaine Diazepam Aspirin Lidocaine None 3. Acidic drugs mainly bind to plasma Albumin Alpha 1 acid glycoprotein Both A and B None of the above None 4. Most drug receptors are Small molecules with a molecular weight between 100 and 1000 Lipids arranged in a bilayer configuration Proteins located on cell membranes or in the cytosol DNA molecules None 5. Creatinine clearance is used as a measurement of Renal excretion rate Glomerular filtration rate Active renal secretion Drug metabolism rate None 6. Which tissue has the greatest capacity to bio-transform drugs? Brain Kidney Liver Skin None 7. With regard to distribution of a drug from the blood into tissues Blood flow to the tissues is an important determinant Solubility of the drug in the tissue is an important determinant Concentration of the drug in the blood is an important determinant All of the above are important determinants None 8. The route of drug administration that gives the most rapid onset of the pharmacological effect is Intramuscular injection Intravenous injection Intradermal injection Subcutaneous injection None 9. After peroral administration, drugs generally are absorbed best from the Buccal cavity Stomach Duodenum Rectum None 10. Which of the following drugs is considered to be the agent of choice for anaphylactic reactions? Edrophonium Ipratropium Propantheline None of the above None