Basic Pharmacology I Farrukh Mehmood, Pharm-D, M.Phil, RPh 6 years ago Welcome to AskPharmaTutor Quiz of Basic Pharmacology I Follow the instructions below to attempt the quiz Choose one best option only Follow the timeline After attempting all the questions click on submit to get your result 1. The following are excreted faster in basic urine Weak acids Strong Acids Weak Bases None of the above None 2. A good example of chemical antagonism Heparin & Protamine Protamine & Zinc Heparin & Prothrombin All of the above None 3. Which of the following provides information about the variation in sensitivity of the drug within the population studied? Maximal efficacy Therapeutic index Drug potency Quantal dose response curve None 4. A physical process by which a weak acid becomes less water soluble and more lipid soluble at low pH is Distribution Elimination First pass effect Protonation None 5. Phenylephrine causes Constriction of vessels in the nasal mucosa Increased gastric secretion and motility Increased skin temperature All of the above None 6. Distribution of drugs to specific tissues Is independent of blood flow to the organ Is independent of the solubility of the drug in that tissue Depends on the unbound drug concentration gradient between blood and tissue Has no effect on the half life of the drug None 7. Which of the following drugs may inhibit the hepatic microsomal P450 responsible for warfarin metabolism Cimetidine Ethanol Phenobarbital Rifampin None 8. Which of the following is a phase II drug metabolizing reaction? Acetylation Deamination Hydrolysis Oxidation None 9. All of the following are general mechanism of drug permeation except Aqueous diffusion Aqueous hydrolysis Lipid diffusion Pinocytosis None 10. Which of the following terms best describes a drug that blocks the action of epinephrine at its receptors by occupying those receptors without activating them? Pharmacological Antagonist Partial Agonist Physiological Antagonist Chemical Antagonist None {{#message}}{{{message}}}{{/message}}{{^message}}Your submission failed. The server responded with {{status_text}} (code {{status_code}}). Please contact the developer of this form processor to improve this message. Learn More{{/message}}{{#message}}{{{message}}}{{/message}}{{^message}}It appears your submission was successful. Even though the server responded OK, it is possible the submission was not processed. Please contact the developer of this form processor to improve this message. Learn More{{/message}}Submitting…